Heterogeneity in breast cancer.

Dosimetric Study of Tissue Heterogeneity Correction for Breast Conformal Radiotherapy

Introduction: Heterogeneity correction is an important parameter in dose calculation for cancer patients where it may be cause inaccuracy in dose calculation as a result of different densities of patients. This study studied the impact of dose calculation of breast cancer patients with and without heterogeneity correction. Material and Methods: Twenty breast cancer patients were treated with Th...

Genetic polymorphism of N142D GSTO2 and susceptibility to breast cancer: a meta-analysis

To establish a comprehensive picture of the relationship between glutathione S-transferase omega 2 (GSTO2; MIM: 612314) gene N142D variant (rs. 156697) and breast cancer risk, the present meta-analysis was carried out. Studies published up to July 2012 with information about GSTO2 polymorphism and breast cancer risk were identified using several electronic databases. We identified 4 eligible st...

Cytoplasmic Her2/neu immunohistochemical staining in breast cancer; From a molecular point of view

cardiac damage in left breast cancer patients

Introduction :Today there is general awareness of the potential damage to the heart in left- sided (more than in rightsided) breast cancer radiotherapy.     Material & Method: Historical changes in tumor and heart doses are presented here along with the impact of different RT techniques and volumes. Results: Individual and pharm...

Human papillomavirus and breast cancer in Iran: a meta- analysis

Objective(s):This study aims to investigate the relationship between human papillomavirus (HPV) and breast cancer using meta- analysis. Materials and Methods: Relevant studies were identified reviewing the national and international databases. We also increased the search sensitivity by investigating the references as well as interview with research centers and experts. Finally, quality assess...

A systematic review and meta-analysis on the association of serum and tumor tissue iron and risk of breast cancer

Background: Some studies have investigated the effects of iron on breast carcinogenesis and reported different findings about the association between Fe and breast cancer risk. This study was conducted to estimate this effect using meta-analysis method. Methods: A total of 20 articles published between 1984 and 2017 worldwide were selected through searching PubMed, Scopus, Embase, Web of Scien...